Science behind ECS

The Science Behind How Your Endocannabinoid System Works And Why Cannabinoids Like CBN Work

Cannabinoids like CBN are more than just a trendy wellness fad. Humans have been enjoying the benefits of this compound well before we understood how cannabis compounds worked with our brains. Scientists studying the effects of cannabis on the brain not only discovered the active ingredient (THC), but also where and how it works with the brain. They coined this set or processes the Endocannabinoid system.  

The natural chemicals produced by the body that interact within the endocannabinoid system (or ECS) are called cannabinoids. CBN is one of these hundreds of cannabinoids, and it works by interacting with receptors to regulate important body functions. So how exactly does this happen? Here we’ll uncover the how and why Your Endocannabinoid System Works And Why Cannabinoids Like CBN Work. 

How Cannabinoids Work Differently From Other Neurotransmitters

You may recall from your highschool microbiology class that neurons communicate with each other and with the rest of the body through chemical signals. These neurotransmitters are released to the brain and received all over the body. This process triggers a set of events that allows the messages to be passed along. From hormones to motor control, neurotransmitters act as the pathway that connects your body. 

The endocannabinoid communicates information within the system in a backwards fashion, also called presynaptic. When a neuron is activated, cannabinoids are made on demand from lipids (or fats) stored within the cells. They are released and travel back to the brain where they attach to cannabinoid receptors. Cannabinoids function more like a dimmer switch and limit neurotransmitters that get released. 

Two types of receptors

The two types of ECS receptors are called CB1 and CB2 receptors. Cannabinoid signaling starts when threats to your biological balance emerge. In response, cannabinoids are produced and bind to the receptors, triggering homeostasis throughout the body. Think of the ECS as a system that keeps you balanced and ‘in-the-zone’.

CB1 and CB2 receptors play different roles in the body. CB1 receptors are primarily located in the brain. CB2 receptors and generally present in the immune system and organs. 

The CB1 and CB2 “lock and key”

The easiest way to think about CB1 and CB2 receptors and cannabinoids is what scientists call the “lock and key”.These keys can be produced internally (endogenous) or externally in the cannabis plant or supplemented with CBN (exogenous). Cannabinoid ‘keys’ bind to receptor ‘locks’ to unlock a chemical message along neurons. A cannabinoid unlocking a CB1 or CB2 receptor is called a neurotransmission. 

How was the endocannabinoid system discovered?

Your endocannabinoid system is a complex cell-signaling system that regulates many of your body’s functions related to maintaining homeostasis

It was first identified  in the late 1990s by a team of researchers who were originally studying THC and metabolic pathways. Up until it’s discovery, no one really understood how cannabis worked with the brain on a molecular level that produced effects such as stimulation of the appetite and pain relief.  Research was slowed due to cannabis being classified as a schedule 1 narcotic. 

Initially identified by Allyn Howlett and William Devane, cannabinoid receptors turned out to be far more abundant in the brain than any other type of neurotransmitter receptor. Cannabinoid receptors function as subtle sensing devices, tiny vibrating scanners perpetually primed to pick up biochemical cues that flow through fluids surrounding each cell. 

So why is the endocannabinoid system so important?

A strong ECS contributes to your body’s ability to moderate processes that impact your wellbeing. We wrote a blog post  about ways to keep your ECS functioning and healthy.

One example of regulation of the ECS at work is the regulation of inflammation in the body. While not all inflammation is bad and can actually help to protect the body from infection, inflammation in excess can be harmful. Unnecessary excess inflammation is referred to as chronic inflammation and can damage healthy cells. 

This is where the ECS comes in. When your body senses an imbalance like this, cannabinoids bind to the CB1 and CB2 receptors which trigger a response to calm the inflammation. This is why cannabinoids like CBN are natural anti-inflammatories. 

Why supplement with CBN?

While your body can produce cannabinoids on its own, deficiencies can be common. A vegetarian might supplement their diet with iron and vitamins they don’t get from meat. An athlete supplements protein shakes to give their tired muscles the amino acids they need. Just like with any supplement, CBN can supplement what your body needs. 

CBN is more than just a natural anti-inflammatory. There are numerous processes that your endocannabinoid system controls and balances that are still being researched and uncovered. A few we already know of include:

  • Appetite
  • Pain-sensation
  • Mood
  • stress response
  • Hormones
  • Memory
  • motor control
  • sleep
  • cardiovascular system function
  • muscle formation
  • bone remodeling and growth
  • liver function
  • reproductive system function

All of these functions contribute to your body’s  homeostasis: the stability of your internal environment. Experts believe that maintaining homeostasis is the primary role of the ECS. Supplementing and caring for your ECS is an excellent way to take care of your overall health and wellbeing.

 It can be easy to supplement what your body needs to stay in balance with a routine that includes a cannabinoid supplement like CBN. Those who try CBN oil often find benefits for anti-anxiety, pain management and sleep. All of these are directly linked to a well functioning ECS. 

Right Wellness CBN Oil Tincture

As we continue to monitor the emerging scientific studies of cannabis and cannabinoids, one thing remains clear: a functional cannabinoid system is essential for health. Cannabinoids help us to survive and adapt to changing external conditions throughout our lifetime. Ingestible cannabinoids are growing in popularity, especially with those who prefer to steer aware from inhalable medication. 

The Right Wellness CBN Oil tincture can be taken orally, and is an easy way to supplement extra cannabinoids in your diet. MCT oil is used as the carrier oil, which has the healthy lipids needed to support a healthy endocannabinoid system and brain. Just like you would supplement an iron supplement if your body wasn’t producing enough, you can easily add a supplement like this. However, when it comes to taking good care of your endocannabinoid system, the pay off is substantial when you consider the wide range of functions you are supporting alongside it. 

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How do I use Right?

Because everyone is different, Right comes in a variety of strengths and dosages. Here are some recommendations for first-timers to help you feel the relief.

Start slow and low

Start small, increasing dosage to your comfort, and make sure to track your doses to ensure you have an idea of how you’ll react.

See how you feel

Take note of your mood, aches and pains, or sleep quality. Do you notice if anything has changed? Feeling more comforted? More relaxed?

Be consistent

It’s best to take Right at the same time every day in the beginning. Try taking note of your dose, time of day, how you feel before and after taking it.

CBN Tincture

Made with the highest quality CBN extracted and refined from US grown hemp. Right Tincture is a simple blend of high quality hemp CBN, organic MCT oil and Vitamin E oil and was designed to be orally ingested.


  • Organic MCT (medium-chain triglyceride) oil
  • CBN Hemp Extract
  • Vitamin E Oil

Dosage Instructions